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Chinmoy Sankar Dey
Professor,
Kusuma School of Biological Sciences
Indian Institute of Technology Delhi,
Hauz Khas, New Delhi 110016, India.
Ph: 91-11-26597523
Email: csdey@bioschool.iitd.ac.in

Education:
1982 B. Sc. (Zoology) Calcutta University, India
1984 M. Sc. (Zoology) Calcutta University, India
1990* Ph. D. (Science) Jadavpur University, India (*Thesis submitted in 1988)

Current  Research Interests

1.  Insulin resistant (Type 2) diabetes: Molecular  mechanism(s), Signal transduction, target(s) identification.

2. Drug resistance in  Leishmania: Molecular  mechanism(s) / target(s)  identification

 Experience

Research 

Indian Institute of Chemical Biology, Calcutta, India            

Ph.D. Fellow

1984 -1988

California Institute of Technology, California, USA               

Postdoctoral Research Fellow

1988 - 1991

Baylor College of Medicine, Texas, USA                              

Postdoctoral Research Associate

1991 - 1992

National Institute of Immunology, New Delhi, India                          

Pool Officer

1992 - 1994

National Institute of Pharmaceutical Education and Research, Punjab, India

Assistant Professor, Dept. Biotechnology

1994 – 1999

National Institute of Pharmaceutical Education and Research, Punjab, India                                                                        

Associate Professor, Dept. Biotechnology

1999 - 2002

National Institute of Pharmaceutical Education and Research,  Punjab, India                                                                    

Professor, Dept. Biotechnology

2002 - 2010

National Institute of Pharmaceutical Education and Research, Punjab, India                                                                       

Head, Department of Biotechnology

2004 - 2010

 

TEACHING EXPERIENCE : 12 years (1998-till date)

PUBLICATIONS   

  • Primary papers: 60  

  • Reviews: 6

  • Book Chapter: 2

  • Patents  granted : 1  USPTO

AWARDS AND HONORS:  

·         SHANTI SWARUP BHATNAGAR AWARD  2003  from Council of Scientific and Industrial Research, Govt. of India, New Delhi.

·         NATIONAL BIOSCIENCE AWARD 2003 from the Department of Biotechnology, Ministry of Science and Technology, Govt. of India, New Delhi. 

·         Organization of Pharmaceutical Producers of Indai-2005 "Scientist" award in “Pharmaceutical Biotechnology”.

·         CDRI  Award in “Excellence in Drug Research in Life Sciences, 2008” from Central Drug Research Institute, Luckhnow.

·         Fellow of the National Academy, (FNA), Indian National  Science Academy (INSA), New Delhi., 2007.

·         Fellow of the National  Academy of Sciences (FNASc), India, 2007.

·         J.C.Bose Fellowship from the Department of Science and Technology, Govt. of India; 2008

·         Press Release in Nature: News India

·         Hottest 25 Papers: Science Direct: Molecular and Biochemical Parasitology, 141, 1, 2005

·         Cover Page: Molecular and Biochemical Parasitology, 141, 1, 2005

·         BMC Cell Biology, 2008, 9: 48: 1408 pdf reprints downloaded within 3 months of publication

 CONSULTANCY (Pharmaceutical  company):  

·         Orchid Chemicals and Pharmaceutical Ltd., Chennai

·         Scientific Advisor, Chembiotek Research International Pvt. Ltd., Kolkata, 2005-2006.

·         DSM Anti Infectives, Punjab                                                

 

JOURNAL EDITORIAL BOARD:

 

  • Regional Associate Editor, Journal of Biopharmaceutics and Biotechnology, USA. (2006)

  • Member, Editorial Board, Open Parasitology Journal, Bentham Publisher (2007-till date).

 

 PUBLICATIONS (Representatives of research areas of last 5 years): 

1              Sharma S, Singh G, Chavan HD, and Dey CS. Proteomic analysis of wild type and arsenite resistant Leishmania donovani. Exp Parasitol. 2009, 123. 

2              Gupta A and Dey CS: PTEN and SHIP2 regulates PI3K/ Akt pathway through Focal adhesion kinase. Mol. Cell. Endocrionol. 2009, 123:55. 

3              Singh GM, Thakur M, Chakraborti  PK and Dey CS: Evidence for the presence of R250G mutation at the ATPase domain of Topoisomerase II in an arsenite-resistant L. donovani that exhibits differential drug inhibition profile. Int. J. Antimicrob. Agents 2009, 33: 80. 

4              Bisht B and Dey CS:  Focal Adhesion Kinase contributes to insulin-induced actin reorganization into a mesh harboring Glucose transporter-4 in insulin resistant skeletal muscle cells.  BMC Cell Biology 2008, 9: 48.  

5              Bisht B, Srinivasan  K and Dey CS. In vivo inhibition of Focal Adhesion Kinase causes insulin resistance. J. Physiology, 2008, 586/16: 3825. 

6              Singh GM , Chavan HD and Dey CS: Proteomic analysis of miltefosine resistant Leishmania reveals the possible involvement of eukaryotic initiation factor 4A,        eIF4A. Int. J. Antimicrob. Agents 2008, 31: 581. 

7              Badiwala, HS, Singh G, Singh, R, Dey CS, Sharma, SS, Bhutani, KK and Singh IP: Antileishmanial amides and lignans from Piper cubeba and Piper retrofractum. J. Nat. Med. 2007, 61: 418.  

8              Singh, G, and Dey CS. Induction of apoptosis-like cell death by pentamidine and doxorubicin through differential inhibition of topoisomerase II in arsenite-resistant L. donovani. Acta Tropica, 2007, 103: 172. 

9              Chavan, HD,  Singh, G and Dey CS. Confocal microscopic investigation of tubulin distribution and effect of paclitaxel on post-translationally modified tubulins in sodium arsenite resistant Leishmania donovani. Exptl. Parasitol. 2007, 116 ; 320. 

10            Bisht, B, Goel, HL and Dey, CS. Focal Adhesion Kinase regulates insulin resistance in skeletal muscle. Diabetologia, 2007, 50:1058. 

11          Verma, NK, Singh, G and  Dey, CS. Miltefosine induces apoptosis in arsenite-resistant Leishmania donovani promastigotes through mitochondrial dysfunction. Exptl. Parasitol., 2006, 116: 1   

12          Singh, J, Verma, NK,  Kansagra Sejal M, Kate, B and Dey, CS. Altered PPARg expression inhibits myogenic differentiation in C2C12 skeletal muscle cells. Mol. Cell. Biochem. 2007, 294: 163. 

13          Verma, NK and Dey, CS. Anti-leishmanial drug miltefosine causes insulin resistance in skeletal muscle cells in vitro.  Diabetologia, 2006, 49:1656.