NeuroDNet

Find a cure for disease

through networks

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Welcome to NeuroDNet

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Query by Disease / Gene / Protein / SNP / Pathway
Construct Network
Disease Models in SBML
Boolean Analysis tool

About NeuroDNet

NeuroDNet is an open source platform for constructing and analyzing neurodegenerative disease associated gene networks. This database was created to provide an interactive platform for researchers in the field to interrogate the relationship between genes implicated in neurodegenerative disorders. The current version of database includes twelve neurodegenerative diseases - Adrenomyeloneuropathy, Alzheimer disease, Amyotrophic lateral sclerosis, Ataxia-telangiectasia, Dentatorubral-pallidoluysian atrophy, Friedreich Ataxia, Frontotemporal Dementia, Huntington disease, Lewy Body Dementia, Parkinson disease, Prion disease, Progressive Supranuclear Palsy (Vasaikar et al. (2013) BMC Neuroscience).

(Last update : 01 August 2016)

Learn more about NeuroDNet

Construct Network

A new graphical tool for Disease gene network interaction analysis merged with NeuroDNet. A webserver for analysing deleterious mutations by molecular dynamics and simulation (ANGDelMut).

NEWS - Seizures and Epileptiform Activity in the Early Stages of Alzheimer Disease (Vossel et al. 2013, JAMA Neurology), Functional networks in brain and their relationship to Alzheimer's ohenotype (Lehmann et al. 2013, PNAS), Loss of inhibitory GABAergic activity overstimulates excitatory neurons, leading to glutamate toxicity in ALS (Foerster et al. 2013, JAMA Neurology), Proliferation of amyloid-?42 aggregates occurs through a secondary nucleation mechanism (Cohen et al. 2013, PNAS).

Adrenomyeloneuropathy
Alzheimer disease
Amyotrophic lateral sclerosis
Ataxia-telangiectasia
Dentatorubral-pallidoluysian atrophy
Friedreich Ataxia
Frontotemporal Dementia
Huntington disease
Lewy Body Dementia
Parkinson disease
Prion disease
Progressive Supranuclear Palsy

NeuroDNet is supported by

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School of Biological Sciences

Systems biology group

IIT Delhi

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