Find a cure for disease
through networks
Over 90,000 coding non-synonymous SNPs (single nucleotide polymorphisms) have been identified in the human genome. SNPs may alter protein function and consequently the gene regulatory network, and thus contribute to variation in disease susceptibility, drug efficacy, and drug toxicity. Identifying key nodes (genes/proteins) in the disease-perturbed networks may provide insights into disease mechanism and the discovery of effective drug targets. The SNPs option of this database contains information collected from the literature on clinical patient data and it gives the user an opportunity to analyze the effect of different SNPs on gene regulation and pathways using the "network model" feature.


( Example : rs63750264 )

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