A shrinking global community means that outbreaks of emerging viral infections are no longer limited by geographical barriers. Understanding how viruses interact with the host cells, how they disassemble to release their genome and assemble into progeny virions, and how they subvert the host surveillance systems is required not only to elucidate the molecular basis of virus-host interaction, but also for developing strategies for prevention and cure. The Structural and Molecular Virology laboratory at the Kusuma School of Biological Sciences, IIT Delhi utilizes a combination of cryo-electron microscopy, molecular dynamics simulations and biophysical techniques to decipher the structural, functional and immunological features of macromolecular interactions during viral infections. Our laboratory also utilizes the knowledge of virus structure and dynamics to engineer virus particles into nano-containers for biomedical delivery. The laboratory has access to a High Performance Computing Cluster, as well as a 200 kV screening microscope and a Titan Krios G3i at the Hauz Khas campus of IIT Delhi.